A Review of the Best Smart Drug Modafinil

Smart drugs comprise a group of medications that help improve cognitive functions in individuals. The best smart drugs help in preserving brain functions, which is especially helpful in treatment of age related degenerative disorders including Parkinson and Alzheimer.

Modafinil is an effective supplement that has been touted by medical experts due to its efficacy and safety. In this article, we will take a detailed look at the medications available for treating various ailments.


Modafinil is a prescription stimulant that is also known by its brand name Provigil. Doctors usually prescribe the medication for treatment of a sleeping disorder called narcolepsy. The sleeping disorder is characterized by excessive sleepiness. FDA has approved the use of Modafinil in the US for treatment of this disorder.

Initially, the mechanism of the action was not known to the researchers. However, later studies found that the medication works as a selective atypical dopamine reuptake inhibitor. Individuals that take the medication feel fully awake and alert and are able to perform the cognitive tasks without felling sleepy. The medication increases the ability of the individual to work with improved focus on concentration.

Studies conducted to test the efficacy of smart drugs have revealed various other benefits besides treatment of sleeping disorder. Apart from the use of medication for treatment of narcolepsy, Modafinial has also found off-label use for treating different medical conditions including depression, chronic fatigue, myotic dystophy, spastic cerebral palsy, and age-related degenerative diseases.

According to Ruairidh McLennan Battleday, who is a professor at the University of Oxford, Modafinil leads to enhanced thinking. The effect of the medication in boosting cognition has been proved in a number of studies conducted since 2008. Neuropsychology professor at Cambridge, Barbara Sahakian, says that the medication drug, which at the moment is only approved for treatment of narcolepsy, can also help in

  • improving working memory,
  • enhancing motivation, and
  • planning in healthy individuals.

This view is shared by Dr. David Dinges, who heads the Sleep and Chronobiology Division at the University of Pennsylvania, who says that Modafinil might be also effective in making the brain work faster (and efficiently) in individuals that are not facing any brain disorders.

Is Modafinil Safe for Consumption?

Modafinil is approved by drug regulatory authorities, which means it is generally safe for consumption. However, there are certain side effects related to the condition. More than 70% of the studies that had studied the efficacy and safety of the medication had found instances of headaches, insomnia, nausea, and stomach aches.

Overall, most smart drug reviews concluded that the medication has been safe and effective cognitive enhancer in controlled condition. The view of Modafinil has been perfectly summed up by Anna-Katharine Brem who wrote in an article published in European Neuropsychopharmacology journaly that “Modafinil seems to be the first ‘smart drug’ that is reasonably safe for healthy people.”

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